Israeli leaders said they carried out a series of preemptive strikes on Iranian nuclear facilities and key personnel early Thursday evening, declaring a national state of emergency as it prepares for anticipated Iranian retaliation.

U.S. officials took steps to distance themselves from the Israeli strikes, emphasizing that it was not involved.

Israelis were instructed to stay close to protected spaces and avoid gatherings, educational activities have been canceled and the Israeli airspace has been closed. 

The Israeli Embassy in Washington issued a statement that Israel had launched a “preemptive, precise, combined offensive to strike Iran’s nuclear program,” and that Israeli jets had been involved in the “first stage” targeting “dozens of military targets, including nuclear targets in different areas of Iran.”

“Today, Iran is closer than ever to obtaining a nuclear weapon. Weapons of mass destruction in the hands of the Iranian regime are an existential threat to the state of Israel and to the wider world,” the statement reads. “The State of Israel has no choice but to fulfill the obligation to act in defense of its citizens and will continue to do so everywhere it is required to do so, as we have done in the past.”

In a prerecorded statement, Israeli Prime Minister Benjamin Netanyahu said that the operation, named “Rising Lion,” was aimed at “rolling back the Iranian threat to Israel’s very survival,” and would “continue for as many days as it takes to remove this threat.”

He said that Israel had targeted Iran’s nuclear enrichment and weaponization program, its enrichment facility in Natanz, its leading nuclear scientist working on the bomb and its ballistic missile program.

Netanyahu said that Iran has amassed enough uranium for nine atomic bombs in recent years, and taken “steps it has never taken before … to weaponize this enriched uranium” and if not stopped, could produce a nuclear weapon within a few months.

“When enemies vow to destroy you, believe them. When enemies build weapons of mass destruction, stop them,” Netanyahu said. “As the Bible teaches us, when someone comes to kill you, rise and act first. This is exactly what Israel has done today. We have risen like lions to defend ourselves.”

Secretary of State Marco Rubio said in a statement the U.S. did not participate in the strikes and urged Iran not to retaliate against American targets.

“Tonight, Israel took unilateral action against Iran. We are not involved in strikes against Iran and our top priority is protecting American forces in the region. Israel advised us that they believe this action was necessary for its self-defense. President Trump and the Administration have taken all necessary steps to protect our forces and remain in close contact with our regional partners. Let me be clear: Iran should not target U.S. interests or personnel,” Rubio said.

Just hours before the strikes, President Donald Trump said on social media the U.S. remains “committed to a Diplomatic Resolution to the Iran Nuclear Issue!” and “They could be a Great Country, but they first must completely give up hopes of obtaining a Nuclear Weapon.”

Dana Stroul, the former deputy assistant secretary of defense for the Middle East under President Joe Biden and the research director at the Washington Institute for Near East Policy, said the strike “appears to be the first wave of an Israeli campaign.”

“The initial target set in downtown Tehran, including what appear to be precise strikes at the residences of senior officials, suggests an intent to paralyze the leadership and command and control of the regime,” Stroul told Jewish Insider. “Follow-on sets of targets could be much broader and geographically diverse.”

The strikes come a day after the International Atomic Energy Agency voted to censure Iran for noncompliance with nonproliferation obligations.

“The Iranian regime appears to have grievously misunderestimated Israeli intent — in a post-Oct. 7 environment, the Israelis were not going to sit back and wait while Iran took additional aggressive steps in its nuclear program as the IAEA definitively confirmed its noncompliance,” Stroul added. “What remains unclear is whether or not President Trump gave the greenlight only days before his envoy Steve Witkoff was supposed to travel back to the region for another round of nuclear negotiations.”

Trump’s self-imposed two-month deadline for nuclear talks expired this week.

Stroul said that Rubio’s comments were “stunning.”

“The American secretary of state is unambiguously stating publicly that Israel made its decision on its own,” she explained. “When Rubio says: Iran should not target U.S. personnel or U.S. interests, there is a very real risk that the Iranians implicitly understand this as a green light to directly attack Israel. What is left unsaid is whether or not the United States will actively participate in the defense of Israel as it did when Iran directly attacked in April and October of last year.”

She said the “ambiguity or suggestion of daylight between the United States and Israel runs the risk of emboldening adversaries.”