Eight Israelis were killed by Iranian missile strikes in five locations that occurred Sunday night and early Monday morning.

In the central Israeli city of Petach Tikva, five people were killed in a residential building, and in adjacent Bnei Brak, an 80-year-old man was found dead at the site of a missile strike.

Two of the people killed in Petach Tikva were inside their safe room, which was directly hit by a missile. Israel’s Home Front Command explained that safe rooms are built to protect from shrapnel, shards and shock waves, but not a direct hit, which is a rare occurrence. The Home Front Command emphasized that everyone else in the building who was in a safe room was not even injured. Petach Tikva Mayor Rami Grinberg said that the residence was struck by a ballistic missile carrying hundreds of kilograms of explosives.

Tel Aviv sustained two direct missile strikes, one of which lightly damaged the U.S. Embassy Branch Office. U.S. Ambassador to Israel Mike Huckabee clarified that “the minor damage to the property were from the shock waves … from the nearby blast … No injuries, thank God!” 

Among the residents evacuated from buildings in Tel Aviv was a six-day-old baby, whose mother was found minutes later.  

In Haifa, three people were found dead under the rubble of a burning building where a missile hit, and about 300 people were evacuated. The Israel Electric Corporation said that the strike damaged its power grid, and that “teams are working on the ground to neutralize safety hazards, in particular the risk of electrocution.” Maritime risk assessment company Ambrey reported a fire at the Haifa Port. 

Israel continued to intercept Iranian and Houthi drones heading to Israel’s north on Monday morning.

About 50 Israeli fighter jets and aircraft struck some 100 military targets in Isfahan in central Iran overnight, the IDF Spokesperson’s Office said on Monday.

Among those targets were missile storage sites, surface-to-surface missile launchers and command centers. Israel has destroyed over 120 missile launchers since the beginning of the operation, about a third of Iran’s total launchers. In one strike overnight, the IAF identified an attempt to launch missiles towards Israel in real time and destroyed the cell and missiles.

The IDF confirmed on Monday that it killed the head of Islamic Revolutionary Guard Corps intelligence Mohammad Kazemi and his deputy, Hassan Mohaqiq, on Sunday. 

The IDF also struck a command center of the Quds Force, part of the IRGC, for the first time, according to the IDF spokesperson. The Quds Force “planned acts of terror against Israel through the Iranian regime’s proxies in the Middle East.”

Israel also reportedly struck near nuclear sites in Fordow. The Wall Street Journal reported that parts of the underground nuclear enrichment site in Natanz collapsed as a result of Israeli strikes.

The IAF struck Mashhad, in eastern Iran, on Sunday afternoon, destroying an Iranian refueling aircraft. Mashhad, some 2300 km (1429 mi) away from Israel, is the farthest Israeli fighter jets have flown in Iran, and, according to some experts, the farthest in any Israeli operation, ever.

The Israeli Navy used a new air defense system called Thunder Shield and LRAD long-range interceptors on Sa’ar 6 ships to intercept eight Iranian drones overnight. The seaborne systems, which have intercepted some 25 projectiles since the beginning of Operation Rising Lion on Thursday night, are able to intercept UAVs, cruise missiles, sea-to-land missiles and more.

Also Monday, the death toll rose to eight from an Iranian strike on Bat Yam, a city south of Tel Aviv. The total number of Israeli fatalities since the beginning of the operation rose to 24 with almost 600 injured. Iran has shot around 350 missiles at Israel.

The Iranian Health Ministry claimed on Sunday that 224 people had been killed since Israel’s operation began Friday with another 1,277 people hospitalized.